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Article

Estrogen receptor gene variants are associated with anxiety disorders in older women.

Psychoneuroendocrinology - 1 Nov 2011

Ryan Joanne, Scali Jacqueline, Carrière Isabelle, Scarabin Pierre-Yves, Ritchie Karen, Ancelin Marie-Laure

Abstract excerpt

BACKGROUND: Estrogen is thought to play a key role in anxiety, but it remains unknown whether genetic variants in the estrogen receptors (ERs) can influence the risk of anxiety. This study investigated whether ESR1 and ESR2 gene variants were associated with specific anxiety disorders in postmenopausal women and evaluated the potential modifying effect of hormone treatment (HT) on these associations. METHODS: One...

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Source

Identifiers

PMID: 21570196
DOI: 10.1016/j.psyneuen.2011.04.011

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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