Article
Association of polymorphisms of the estrogen receptor gene with anxiety-related traits in children and adolescents: a longitudinal study.
American journal of medical genetics - 8 Mar 2002
Prichard Zoë, Jorm Anthony F, Prior Margot, Sanson Ann, Smart Diana, Zhang Yafei, Huttley Gavin, Easteal Simon
Abstract excerpt
Anxiety problems and associated temperamental traits are multifactorial, determined by the interaction of genetic and environmental factors. Genetic effects may involve both neurotransmitters and hormones. A good candidate gene for association with anxiety-related traits is the estrogen receptor (ESRalpha). Estrogen exerts an effect on mood and behavior in humans through gene regulation on binding to estrogen...
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