Article
Risks of Melanoma and Other Cancers in Melanoma-Prone Families over 4 Decades.
The Journal of investigative dermatology - 1 Jul 2018
Tucker Margaret A, Elder David E, Curry Michael, Fraser Mary C, Pichler Virginia, Zametkin Deborah, Yang Xiaohong R, Goldstein Alisa M
Abstract excerpt
Since 1976, melanoma-prone families have been followed at the National Cancer Institute to identify etiologic factors for melanoma. We compared risks of melanoma and other cancers in 1,226 members of 56 families followed for up to 4 decades with population rates in the Surveillance, Epidemiology, and End Results program. All families were tested for mutations in CDKN2A and CDK4; 29 were mutation-positive and 27...
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