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Article

Novel multiplex bead-based assay with LNA-modified probes for detection of MPL exon 10 mutations.

Leukemia research - 1 Aug 2011

Ivanova Milena I, Shivarov Velizar S, Hadjiev Evgueniy A, Naumova Elissaveta J

Abstract excerpt

MPL exon 10 mutations were the second class of mutations shown to be associated with the pathogenesis of some Philadelphia chromosome - negative myeloproliferative neoplasms (MPNs). Recently, their identification gained wide recognition in the diagnostic work-up for suspected cases of JAK2 V617F negative MPNs. Various molecular approaches have been applied, yet universally accepted method is still lacking. We...

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Source

Identifiers

PMID: 21570117
DOI: 10.1016/j.leukres.2011.04.012

Genes

MPL
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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