Article
PNA-FISH as a new diagnostic method for the determination of clarithromycin resistance of Helicobacter pylori.
BMC microbiology - 14 May 2011
Cerqueira Laura, Fernandes Ricardo M, Ferreira Rui M, Carneiro Fátima, Dinis-Ribeiro Mário, Figueiredo Céu, Keevil Charles W, Azevedo Nuno F, Vieira Maria J
Abstract excerpt
BACKGROUND: Triple therapy is the gold standard treatment for Helicobacter pylori eradication from the human stomach, but increased resistance to clarithromycin became the main factor of treatment failure. Until now, fastidious culturing methods are generally the method of choice to assess resistance status. In this study, a new genotypic method to detect clarithromycin resistance in clinical samples, based on...
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