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Simultaneous Detection of Helicobacter pylori and Clarithromycin Resistance Mutations Using RAA-CRISPR/Cas13a Assay

1 Jul 2024

Abstract excerpt

Background: Infection caused by Helicobacter pylori ( H. pylori ) affects approximately 50% of the global population. It is a major pathogenic factor for chronic gastritis and gastric cancer. Besides, the resistance to antibiotics such as clarithromycin could reduce the eradication rate. Currently, there is an urgent need for a swift, easy to perform, and highly sensitive detection method for H. pylori and...

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PMID: 39045109
DOI: 10.2147/idr.s462963

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