Article
Multiplex fluorescent PCR-based detection of Helicobacter pylori nucleic acid and antibiotic resistance genes in clinical stool samples: a performance evaluation from Gansu Province, China.
BMC infectious diseases - 29 Apr 2026
Dong Yeze, Yang Jinxia, Xie Baoyuan, Wang Yuanyuan, Chen Xinglan, Zhang Dekui
Abstract excerpt
BACKGROUND: The increasing antibiotic resistance of Helicobacter pylori (H. pylori) undermines empirical treatment efficacy. Rapid, non-invasive methods simultaneously detecting H. pylori and resistance mutations are needed. However, the clinical performance of multiplex fluorescent PCR kits on stool samples in Chinese populations remains under-evaluated. METHODS: A total of 535 patients with suspected H. pylori...
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