Article
Prevalence of single nucleotide mutation in clarithromycin resistant gene of Helicobacter pylori: a 32-months prospective study by using hybridization real time polymerase chain reaction.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Mar 2012
Hansomburana Piyathida, Anantapanpong Siriwat, Sirinthornpunya Siam, Chuengyong Kitti, Rojborwonwittaya Jarin
Abstract excerpt
Polymerase chain reaction (PCR) for detection of single nucleotide mutations in 23S rRNA gene of clarithromycin resistance Helicobacter pylori were investigated worldwide. In Thailand, the prevalence of these mutations had not been extensively investigated. The authors conducted a 32-months prospective study to estimate the prevalence of clarithromycin resistant Helicobacter pylori and to compare the sensitivity...
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