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Article

Depression of humoral responses by murine cytomegalovirus infection.

Immunology and cell biology - 1 Feb 1990

Price P

Abstract excerpt

The ability of mice infected with murine cytomegalovirus (MCMV) to respond to unrelated antigens in vivo was studied in genetically sensitive BALB/c and genetically resistant CBA mice. Suppressed humoral responses were observed following intraperitoneal or intravenous antigen challenge a few days after infection. IgG production was depressed more frequently than IgM. The suppression was correlated with splenic...

Topics

Animals
Antibody Formation
Cytomegalovirus Infections
Female
H-2 Antigens
Immune Tolerance
Immunocompetence
Mice
Mice, Inbred BALB C
Mice, Inbred CBA
Ovalbumin
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Povidone

Spleen

Source

Identifiers

PMID: 2156775
DOI: 10.1038/icb.1990.5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2156775-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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