Murine cytomegalovirus independently inhibits priming of helper and cytotoxic T lymphocytes.

doi:10.1016/0042-6822(91)90761-y

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Article

Murine cytomegalovirus independently inhibits priming of helper and cytotoxic T lymphocytes.

Virology - 1 Nov 1991

Slater J S, Futch W S, Cavanaugh V J, Campbell A E

Abstract excerpt

Murine cytomegalovirus (MCMV) inhibits antigen-specific cytotoxic T lymphocyte (CTL) priming in vivo (Campbell et al., 1989). To address the mechanism of this immune suppression, two possibilities were considered: (1) MCMV directly interferes with in vivo priming of CTL precursors (CTLp), or (2)...

Topics

Animals
CD4 Antigens
Cell Line
Cell Line, Transformed
Cytomegalovirus
Cytomegalovirus Infections
Interleukin-2
Interleukin-4
Lymph Nodes
Lymphocyte Depletion
Male
Mice
Mice, Inbred BALB C
Phenotype
Recombinant Proteins
Simian virus 40
T-Lymphocyte Subsets
T-Lymphocytes, Cytotoxic

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Identifiers

PMID: 1656582
DOI: 10.1016/0042-6822(91)90761-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1656582-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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