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Article

Phenotypic and functional characterization of CD8(+) T cell clones specific for a mouse cytomegalovirus epitope.

Virology - 1 Mar 1999

Fernandez J A, Zavala F, Tsuji M

Abstract excerpt

A series of CD8(+) T cell clones, specific for the IE1 epitope YPHFMPTNL, of the immediate-early protein 1 of the murine cytomegalovirus (MCMV) were generated in order to determine their protective activity against this infection and correlate their phenotypic markers with antiviral activity. We found that the adoptive transfer of three of these anti-MCMV CD8(+) T cell clones into irradiated naive mice resulted...

Topics

Animals
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Clone Cells
Epitopes, T-Lymphocyte
Female
Herpesviridae Infections
Immediate-Early Proteins
Immunodominant Epitopes
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muromegalovirus

Phenotype

Time Factors

Viral Proteins

Source

Identifiers

PMID: 10049820
DOI: 10.1006/viro.1998.9575

Genes

TNF

Provenance

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