Article
Gene expression and single nucleotide polymorphism array analyses of spindle cell lipomas and conventional lipomas with 13q14 deletion.
Genes, chromosomes & cancer - 1 Aug 2011
Bartuma Hammurabi, Nord Karolin H, Macchia Gemma, Isaksson Margareth, Nilsson Jenny, Domanski Henryk A, Mandahl Nils, Mertens Fredrik
Abstract excerpt
Spindle cell lipomas (SCL) are circumscribed, usually s.c. tumors that typically occur on the posterior neck, shoulder, and back of middle aged men. Cytogenetically, almost all SCL are characterized by deletions of chromosome arm 13q, often in combination with loss of 16q. Deletions of 13q are seen also in approximately 15% of conventional lipomas. Through single nucleotide polymorphism (SNP) array analyses, we...
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