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Article

Ribavirin Can Be Mutagenic for Arenaviruses

12 May 2011

Abstract excerpt

Arenaviruses include several important human pathogens, and there are very limited options of preventive or therapeutic interventions to combat these viruses. An off-label use of the purine nucleoside analogue ribavirin (1-β-d-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide) is the only antiviral treatment currently available for arenavirus infections. However, the ribavirin antiviral mechanism action against...

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PMID: 21561907
DOI: 10.1128/jvi.00614-11

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