Article
The role of urotensin II in the metabolic syndrome.
Peptides - 1 May 2008
Ong Kwok Leung, Wong Louisa Y F, Cheung Bernard M Y
Abstract excerpt
Urotensin II is a potent vasoconstrictive peptide that mediates both endothelium-independent vasoconstriction and endothelium-dependent vasodilatation. Its plasma level correlates positively with body weight and is raised in diabetes, renal failure, hypertension, and other cardiovascular diseases including congestive heart failure and carotid atherosclerosis. It can inhibit glucose-induced insulin secretion, and...
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