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Article

Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor.

PloS one - 29 Apr 2011

Mayor Alfredo, Hafiz Abdul, Bassat Quique, Rovira-Vallbona Eduard, Sanz Sergi, Machevo Sónia, Aguilar Ruth, Cisteró Pau, Sigaúque Betuel, Menéndez Clara, Alonso Pedro L, Chitnis Chetan E

Abstract excerpt

INTRODUCTION: Severe malaria has been attributed partly to the sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the microvasculature of vital host organs. Identification of P. falciparum cytoadherence phenotypes that are associated with severe malaria may lead to the development of novel strategies against life-threatening malaria. METHODS AND FINDINGS: Forty-six P. falciparum isolates from...

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Share to Blood Platelets
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythrocytes

Share to Malaria, Falciparum

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Source

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Identifiers

PMID: 21559373
DOI: 10.1371/journal.pone.0019422
PMCID: PMC3084855

Genes

ICAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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