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Article

Rosetting in Plasmodium vivax: a cytoadhesion phenotype associated with anaemia.

PLoS neglected tropical diseases - 1 Jan 2013

Marín-Menéndez Alejandro, Bardají Azucena, Martínez-Espinosa Flor E, Bôtto-Menezes Camila, Lacerda Marcus V, Ortiz Jon, Cisteró Pau, Piqueras Mireia, Felger Ingrid, Müeller Ivo, Ordi Jaume, del Portillo Hernando, Menéndez Clara, Wahlgren Mats, Mayor Alfredo

Abstract excerpt

BACKGROUND: Plasmodium vivax can potentially lead to life-threatening episodes but the mechanisms underlying severe disease remain poorly defined. Cytoadhesion of infected erythrocytes may contribute to P. vivax sequestration and organ injury although its physiological impact is still unknown. Here, we aimed to describe clinically-relevant cytoadhesive phenotypes of P. vivax isolates. METHODOLOGY/PRINCIPAL...

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Identifiers

PMID: 23593522
DOI: 10.1371/journal.pntd.0002155
PMCID: PMC3617122

Genes

ICAM1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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