Article
Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
Proceedings of the National Academy of Sciences of the United States of America - 13 Feb 2001
Pain A, Ferguson D J, Kai O, Urban B C, Lowe B, Marsh K, Roberts D J
Abstract excerpt
Sequestration of malaria-infected erythrocytes in the peripheral circulation has been associated with the virulence of Plasmodium falciparum. Defining the adhesive phenotypes of infected erythrocytes may therefore help us to understand how severe disease is caused and how to prevent or treat it. We have previously shown that malaria-infected erythrocytes may form apparent autoagglutinates of infected...
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