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Article

CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration.

The British journal of ophthalmology - 1 Feb 2012

McKibbin Martin, Ali Manir, Bansal Shveta, Baxter Paul D, West Kumi, Williams Grange, Cassidy Frances, Inglehearn Chris F

Abstract excerpt

AIMS: To investigate an association between genotype for three single nucleotide polymorphisms strongly associated with the development of age-related macular degeneration (AMD) and the early response to treatment with intravitreal ranibizumab for neovascular AMD. METHODS: Best corrected visual acuity letter score was recorded at baseline and each subsequent visit. Age, sex, smoking history, lesion type and the...

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Source

Identifiers

PMID: 21558292
DOI: 10.1136/bjo.2010.193680

Genes

CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration.PMID 21558292Read ↗

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