Article
VEGF gene polymorphism and response to intravitreal ranibizumab in neovascular age-related macular degeneration.
Ophthalmic research - 1 Jan 2014
Veloso Carlos Eduardo dos Reis, de Almeida Luciana Negrão Frota, Recchia Franco Maria, Pelayes David, Nehemy Márcio Bittar
Abstract excerpt
BACKGROUND/AIMS: To investigate the association between VEGF gene polymorphism and response to ranibizumab in neovascular age-related macular degeneration (AMD). METHODS: A total of 92 patients were genotyped for the VEGF rs1413711 single nucleotide polymorphism. Patients with neovascular AMD initially received 3 monthly ranibizumab intravitreal injections and were retreated as needed. Visual acuity (VA) and...
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