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Article

Genome instability in rad54 mutants of Saccharomyces cerevisiae.

Nucleic acids research - 1 Feb 2003

Schmuckli-Maurer Jacqueline, Rolfsmeier Michael, Nguyen Ho, Heyer Wolf-Dietrich

Abstract excerpt

The RAD54 gene of Saccharomyces cerevisiae encodes a conserved dsDNA-dependent ATPase of the Swi2/Snf2 family with a specialized function during recombinational DNA repair. Here we analyzed the consequences of the loss of Rad54 function in vegetative (mitotic) cells. Mutants in RAD54 exhibited drastically reduced rates of spontaneous intragenic recombination but were proficient for spontaneous intergenic...

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Identifiers

PMID: 12560498
DOI: 10.1093/nar/gkg190
PMCID: PMC149210

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Source receipt: pubmed, retrieved 7 Sept 2026.

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