Article
Variable requirements for herpes simplex virus immediate-early proteins in the expression of the adenovirus E2 gene.
Virology - 1 Mar 1990
Bachenheimer S L, Elshiekh N
Abstract excerpt
Regulation of the adenovirus E2 gene by trans-activating proteins encoded by herpes simplex virus was investigated. Coinfection of Vero cells was performed with Ad5 dl312 (an E1 deletion mutant) and either wildtype HSV, mutant virus encoding a temperature-sensitive ICP4 protein (tsK), or mutants carrying deletions in the ICP4 (d120) or ICP0 (dl x 3.1) gene. As detected by the presence of E2 mRNA, or the product...
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