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Article

Variable requirements for herpes simplex virus immediate-early proteins in the expression of the adenovirus E2 gene.

Virology - 1 Mar 1990

Bachenheimer S L, Elshiekh N

Abstract excerpt

Regulation of the adenovirus E2 gene by trans-activating proteins encoded by herpes simplex virus was investigated. Coinfection of Vero cells was performed with Ad5 dl312 (an E1 deletion mutant) and either wildtype HSV, mutant virus encoding a temperature-sensitive ICP4 protein (tsK), or mutants carrying deletions in the ICP4 (d120) or ICP0 (dl x 3.1) gene. As detected by the presence of E2 mRNA, or the product...

Topics

Adenoviruses, Human
Animals
Chromosome Deletion
DNA-Binding Proteins
Gene Expression Regulation, Viral
Genes, Viral
Immediate-Early Proteins
Mutation
RNA, Messenger
Simplexvirus
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ubiquitin-Protein Ligases

Vero Cells

Viral Proteins

Viral Regulatory and Accessory Proteins

Source

Identifiers

PMID: 2155517
DOI: 10.1016/0042-6822(90)90219-h

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2155517-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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