Article
Genetic diversity of Plasmodium vivax Duffy Binding Protein II (PvDBPII) under unstable transmission and low intensity malaria in Sri Lanka.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2011
Premaratne Prasad H, Aravinda B Ramesh, Escalante Ananias A, Udagama Preethi V
Abstract excerpt
Elucidating the genetic diversity of the Duffy Binding Protein II (PvDBPII), a leading vaccine candidate for vivax malaria, in different geographical settings is vital. In Sri Lanka malaria transmission is unstable with low intensity. A relatively high level of allelic diversity, with 27 polymorp...
Topics
- Adult
- Amino Acid Sequence
- Amino Acid Substitution
- Antigens, Protozoan
- Binding Sites
- Endemic Diseases
- Epitopes, B-Lymphocyte
- Epitopes, T-Lymphocyte
- Genetic Variation
- Haplotypes
- Humans
- Malaria, Vivax
- Molecular Sequence Data