Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypercholesterolemia and a candidate gene within the 12q24 locus.

Cardiovascular diabetology - 9 May 2011

Gragnoli Claudia

Abstract excerpt

BACKGROUND: The 12q24 locus entails at least one gene responsible for hypercholesterolemia. Within the 12q24 locus lies the gene of proteasome modulator 9 (PSMD9). PSMD9 is in linkage with type 2 diabetes (T2D), T2D-nephropathy and macrovascular pathology in Italian families and PSMD9 rare mutations contribute to T2D. AIMS: In the present study, we aimed at determining whether the PSMD9 T2D risk single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol, LDL
Share to Chromosomes, Human, Pair 12
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Hypercholesterolemia

Share to Lod Score

Share to Proteasome Endopeptidase Complex

Source

Open in PubMed Open full text

Identifiers

PMID: 21554682
DOI: 10.1186/1475-2840-10-38
PMCID: PMC3116465

Genes

PSMD9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypercholesterolemia and a candidate gene within the 12q24 locus.PMID 21554682Read ↗

Proteasome modulator 9 SNPs are linked to hypertension in type 2 diabetes families.Semantic proximity Read ↗

Proteasome modulator 9 is linked to microvascular pathology of T2D.Semantic proximity Read ↗

Proteasome modulator 9 and macrovascular pathology of T2D.Semantic proximity Read ↗

T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia.Semantic proximity Read ↗

Proteasome modulator 9 gene is linked to diabetic and non-diabetic retinopathy in T2D.Semantic proximity Read ↗

Proteasome modulator 9 and depression in type 2 diabetes.Semantic proximity Read ↗

PSMD9 is linked to type 2 diabetes neuropathy.Semantic proximity Read ↗

T2D-nephropathy linkage within 12q24 locus.Semantic proximity Read ↗

Proteasome modulator 9 gene SNPs, responsible for anti-depressant response, are in linkage with generalized anxiety disorder.Semantic proximity Read ↗

PSMD9 gene in the NIDDM2 locus is linked to type 2 diabetes in Italians.Semantic proximity Read ↗

Fine-Mapping of the PLCL2 Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome PatientsSemantic proximity Read ↗

8q24.3 and 11q25 chromosomal loci association with low HDL-C in metabolic syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.