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Article

Proteasome modulator 9 is linked to microvascular pathology of T2D.

Journal of cellular physiology - 1 Aug 2012

Gragnoli Claudia

Abstract excerpt

The locus 12q24 is linked to type 2 diabetes (T2D) and to changes in retinal vascular caliber in Caucasians. Proteasome Modulator 9 gene (PSMD9) lies in the 12q24 locus and is implicated in diabetes onset and in degradation of intracellular proteins in antigenic peptides in the immune response to antigen presentation by MHC class I cells. Within PSMD9, we reported a linkage to T2D and to MODY3 in Italian...

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Share to Diabetes Mellitus, Type 2
Share to Genes, Recessive
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Proteasome Endopeptidase Complex

Source

Identifiers

PMID: 22015693
DOI: 10.1002/jcp.23063

Genes

PSMD9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteasome modulator 9 is linked to microvascular pathology of T2D.PMID 22015693Read ↗

Proteasome modulator 9 SNPs are linked to hypertension in type 2 diabetes families.Semantic proximity Read ↗

Proteasome modulator 9 gene is linked to diabetic and non-diabetic retinopathy in T2D.Semantic proximity Read ↗

Proteasome modulator 9 and macrovascular pathology of T2D.Semantic proximity Read ↗

PSMD9 is linked to type 2 diabetes neuropathy.Semantic proximity Read ↗

Hypercholesterolemia and a candidate gene within the 12q24 locus.Semantic proximity Read ↗

Proteasome modulator 9 gene SNPs, responsible for anti-depressant response, are in linkage with generalized anxiety disorder.Semantic proximity Read ↗

Proteasome modulator 9 and depression in type 2 diabetes.Semantic proximity Read ↗

T2D-nephropathy linkage within 12q24 locus.Semantic proximity Read ↗

T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia.Semantic proximity Read ↗

Proteasome modulator 9 and carpal tunnel syndrome.Semantic proximity Read ↗

PSMD9 gene in the NIDDM2 locus is linked to type 2 diabetes in Italians.Semantic proximity Read ↗

PSMD9 is linked to MODY3.Semantic proximity Read ↗

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