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Article

T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia.

Scientific reports - 13 Jul 2015

Hao Han, Haas Michael J, Wu Rongling, Gragnoli Claudia

Abstract excerpt

Insomnia increases type-2 diabetes (T2D) risk. The 12q24 locus is linked to T2D, depression, bipolar disorder and anxiety. At the 12q24 locus, the Proteasome-Modulator 9 (PSMD9) single nucleotide polymorphisms (SNPs) rs74421874 [intervening sequence (IVS) 3+nt460-G>A], rs3825172 (IVS3+nt437-C>T) and rs14259 (E197G-A>G) are linked to: T2D, depression, anxiety, maturity-onset-diabetes-of the young 3/MODY3, obesity,...

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Share to Diabetes Mellitus, Type 2
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Share to Linkage Disequilibrium
Share to Polymorphism, Single Nucleotide
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Share to Sleep Initiation and Maintenance Disorders
Share to Statistics, Nonparametric

Source

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Identifiers

PMID: 26166263
DOI: 10.1038/srep12032
PMCID: PMC4648424

Genes

PSMD9

Provenance

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