Article
PSMD9 gene in the NIDDM2 locus is linked to type 2 diabetes in Italians.
Journal of cellular physiology - 1 Feb 2010
Gragnoli Claudia
Abstract excerpt
Type 2 diabetes (T2D) has a replicated linkage on chromosome12q24.2, the non-insulin-dependent-diabetes 2 (NIDDM2) locus. PSMD9 (which rarely causes T2D in Italians) lies in the NIDDM2 region and is implicated in beta cell insulin transcription and diabetes onset in mice. Thus, PSMD9 is a candidate T2D gene for the NIDDM2 locus. We aimed at identifying any linkage of the PSMD9 A/T/G haplotype, or of any of its...
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