Article
8q24.3 and 11q25 chromosomal loci association with low HDL-C in metabolic syndrome.
European journal of clinical investigation - 1 Oct 2011
Daneshpour Maryam Sadat, Rebai Ahmed, Houshmand Massoud, Alfadhli Suad, Zeinali Sirous, Hedayati Mehdi, Zarkesh Maryam, Azizi Fereidoun
Abstract excerpt
BACKGROUND: High-density lipoprotein cholesterol (HDL-C) levels are low in Iranians. Low HDL-C is the most frequent phenotype in metabolic syndrome (MetS) among the Iranian population (32%). This has been claimed to be related to genetic factors. MATERIALS AND METHODS: To investigate possible genes linked to this disorder, 12 microsatellite markers were selected. They were used in 107 families with MetS and low...
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