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Article

Glioblastoma motility occurs in the absence of actin polymer.

Molecular biology of the cell - 1 Jul 2011

Panopoulos Andreas, Howell Michael, Fotedar Rati, Margolis Robert L

Abstract excerpt

In fibroblasts and keratocytes, motility is actin dependent, while microtubules play a secondary role, providing directional guidance. We demonstrate here that the motility of glioblastoma cells is exceptional, in that it occurs in cells depleted of assembled actin. Cells display persistent motil...

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Identifiers

PMID: 21551075
DOI: 10.1091/mbc.E10-10-0849
PMCID: PMC3128524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21551075-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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