Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Greatwall kinase during Xenopus oocyte maturation.

Molecular biology of the cell - 1 Jul 2011

Yamamoto Tomomi M, Blake-Hodek Kristina, Williams Byron C, Lewellyn Andrea L, Goldberg Michael L, Maller James L

Abstract excerpt

Greatwall kinase has been identified as a key element in M phase initiation and maintenance in Drosophila, Xenopus oocytes/eggs, and mammalian cells. In M phase, Greatwall phosphorylates endosulfine and related proteins that bind to and inhibit protein phosphatase 2A/B55, the principal phosphatase for Cdk-phosphorylated substrates. We show that Greatwall binds active PP2A/B55 in G2 phase oocytes but dissociates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinases
Share to G2 Phase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Signaling Peptides and Proteins

Share to Phosphoprotein Phosphatases

Share to Progesterone

Share to Protein Phosphatase 2

Share to Xenopus

Share to Xenopus Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21551066
DOI: 10.1091/mbc.E11-01-0008
PMCID: PMC3128519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Greatwall kinase during Xenopus oocyte maturation.PMID 21551066Read ↗

Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B.Semantic proximity Read ↗

Greatwall-Endos-PP2A/B55Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo transition.Semantic proximity Read ↗

Mutations in Drosophila Greatwall/Scant reveal its roles in mitosis and meiosis and interdependence with Polo kinase.Semantic proximity Read ↗

Greatwall maintains mitosis through regulation of PP2A.Semantic proximity Read ↗

Suppression of scant identifies Endos as a substrate of greatwall kinase and a negative regulator of protein phosphatase 2A in mitosis.Semantic proximity Read ↗

Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans.Semantic proximity Read ↗

The Balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cellsSemantic proximity Read ↗

PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos.Semantic proximity Read ↗

Characterization of the mechanisms controlling Greatwall activity.Semantic proximity Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.Semantic proximity Read ↗

A late phase of Oskar accumulation is crucial for posterior patterning of the Drosophila embryo, and is blocked by ectopic expression of Bruno.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.