Article
The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.
EMBO molecular medicine - 1 Jul 2016
Kessler Thorsten, Vilne Baiba, Schunkert Heribert
Abstract excerpt
Cardiovascular diseases are leading causes for death worldwide. Genetic disposition jointly with traditional risk factors precipitates their manifestation. Whereas the implications of a positive family history for individual risk have been known for a long time, only in the past few years have genome-wide association studies (GWAS) shed light on the underlying genetic variations. Here, we review these studies...
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