Article
From candidate gene to genome-wide association studies in cardiovascular disease.
Thrombosis research - 1 Mar 2012
Gianfagna Francesco, Cugino Daniela, Santimone Iolanda, Iacoviello Licia
Abstract excerpt
Continuous updating of the genotyping technology has led to improvement of genetic study design. The recent advances in technology coupled with the advances in our understanding of the molecular mechanisms have allowed a more comprehensive examination of the role of genetics, environment and their interaction in determining the individual risk of cardiovascular disease (CVD). Initial candidate gene studies...
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