Article
Antigenic and functional analysis of a neutralization site of HSV-1 glycoprotein D.
Virology - 1 Feb 1990
Muggeridge M I, Wu T T, Johnson D C, Glorioso J C, Eisenberg R J, Cohen G H
Abstract excerpt
Herpes simplex virus glycoprotein D is a component of the virion envelope and appears to be involved in attachment, penetration, and cell fusion. Monoclonal antibodies (MAbs) against this protein can be arranged in groups, on the basis of a number of biological and biochemical properties. Group I antibodies are type-common, have high complement-independent neutralization titers, recognize discontinuous...
Topics
- Base Sequence
- Cloning, Molecular
- Genes, Viral
- Genetic Complementation Test
- Glycosylation
- Molecular Sequence Data
- Mutation
- Neutralization Tests
- Recombination, Genetic
- Simplexvirus
- Viral Envelope Proteins