Article
Polyomavirus JC reactivation and noncoding control region sequence analysis in pediatric Crohn's disease patients treated with infliximab.
Journal of neurovirology - 1 Aug 2011
Bellizzi Anna, Anzivino Elena, Ferrari Federica, Di Nardo Giovanni, Colosimo Maria Teresa, Fioriti Daniela, Mischitelli Monica, Chiarini Fernanda, Cucchiara Salvatore, Pietropaolo Valeria
Abstract excerpt
The recent introduction of monoclonal antibodies in Crohn's disease (CD) management has been associated with the development of serious complications, such as the progressive multifocal leukoencephalopathy (PML), caused by JC polyomavirus (JCV) reactivation. Therefore, the aims of our study have been the investigation of the possible JCV reactivation in pediatric CD patients treated or not with infliximab,...
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