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Article

Increased frequency of JC-polyomavirus detection in rheumatoid arthritis patients treated with multiple biologics.

Medical microbiology and immunology - 1 Oct 2015

Verheyen Jens, Maizus Kseniya, Feist Eugen, Tolman Zebulon, Knops Elena, Saech Jasemine, Spengler Lydia, Waterboer Tim, Burmester Gerd R, Pawlita Michael, Pfister Herbert, Rubbert-Roth Andrea

Abstract excerpt

Progressive multifocal leukoencephalopathy (PML) represents a rare but potentially fatal reactivation of JC-polyomavirus (JCPyV) recently also reported in patients with autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis (RA) treated with rituximab. The aim of the present study was to analyse the pattern of JCPyV infections in patients with RA undergoing treatment with biologic...

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Identifiers

PMID: 25678083
DOI: 10.1007/s00430-015-0390-5

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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