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Genetics and orofacial clefts: a clinical perspective

23 Jun 2023

Abstract excerpt

Orofacial clefts (OFCs) are the most common congenital craniofacial anomaly seen in humans. Most OFCs are sporadic and isolated - these are thought to be multifactorial in origin. Chromosomal and monogenic variants account for the syndromic forms and for some of the non-syndromic inherited forms. This review discusses the importance of genetic testing and the current clinical strategy to deliver a genomics...

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PMID: 37349452
DOI: 10.1038/s41415-023-5994-3

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