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Article

Genetic models and approaches to study orofacial clefts.

Oral diseases - 1 Jul 2022

Leslie Elizabeth J

Abstract excerpt

INTRODUCTION: Orofacial clefts (OFCs) are common craniofacial birth defects with heterogeneous phenotype and etiology. Geneticists have applied nearly every available method and technology for further understanding of the genetic architectures of OFCs. OBJECTIVE: This review describes the evidence for a genetic etiology in OFCs, statistical genetic approaches employed to identify genetic causes, and how the...

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PMID: 34923716
DOI: 10.1111/odi.14109

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