Article
Correlation between circulatory, local prostatic, and intra-prostatic androgen levels.
The Prostate - 15 Jun 2011
Olsson Mats, Ekström Lena, Guillemette Chantal, Belanger Alain, Rane Anders, Gustafsson Ove
Abstract excerpt
BACKGROUND: Testosterone is converted to the more potent androgen dihydrotestosterone (DHT) in the prostate. DHT and androgen metabolites are inactivated by uridine diphospho (UDP)-glucuronosyl transferase (UGT) enzymes. Here we have studied the influence of the prostate gland on the systemic levels of DHT. Moreover, genetic variation in androgen metabolizing UGT enzymes and the intra-prostatic levels of...
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