Article
Auditory verbal working memory load and thalamic activation in nonpsychotic relatives of persons with schizophrenia: an fMRI replication.
Neuropsychology - 1 Sept 2007
Seidman Larry J, Thermenos Heidi W, Koch Jennifer K, Ward Michael, Breiter Hans, Goldstein Jill M, Goodman Julie M, Faraone Stephen V, Tsuang Ming T
Abstract excerpt
First-degree relatives of persons with schizophrenia are at genetic risk for the illness and show deficits on high-load information-processing tasks. In a prior study of auditory working memory (WM) using functional MRI (fMRI), the authors demonstrated that adult relatives had significantly increased activation in the dorsomedial (DM) thalamus, anterior cingulate, and prefrontal cortex (H. W. Thermenos et al.,...
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