Article
The research on the immuno-modulatory defect of mesenchymal stem cell from Chronic Myeloid Leukemia patients.
Journal of experimental & clinical cancer research : CR - 2 May 2011
Xishan Zhu, Guangyu An, Yuguang Song, Hongmei Zhang
Abstract excerpt
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not found in the majority of the leukemic cells. These leukemic stem cells are necessary and sufficient to...
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