Article
Functional mesenchymal stem cells remain present in bone marrow microenvironment of patients with leukemia post-allogeneic hematopoietic stem cell transplant.
Leukemia & lymphoma - 1 Jul 2014
Ding Li, Zhu Heng, Yang Yang, Wang Zhi-Dong, Zheng Xiao-Li, Yan Hong-Min, Dong Lei, Zhang Hai-Hong, Han Dong-Mei, Xue Mei, Liu Jing, Zhu Ling, Guo Zi-Kuan, Wang Heng-Xiang
Abstract excerpt
Mesenchymal stem cells (MSCs) and their progenies are important supporting cells in the bone marrow (BM) microenvironment. However, the function and kinetics of MSCs post-hematopoietic stem cell transplant (HSCT) remain unknown. In the present study, MSCs were cultured from a total of 76 BM samples from 15 patients receiving HSCT. Colony-forming unit fibroblasts in BM before pre-conditioning and 1, 3, 6 and 9...
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