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Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics

22 Mar 2005

Abstract excerpt

Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not found in the majority of the leukemic cells. These leukemic stem cells are necessary and sufficient to...

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PMID: 15591120
DOI: 10.1182/blood-2004-07-2514

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