Article
Whole-genome genotyping of haplotype tag single nucleotide polymorphisms.
Pharmacogenomics - 1 Jun 2006
Gunderson Kevin L, Kuhn Kenneth M, Steemers Frank J, Ng Pauline, Murray Sarah S, Shen Richard
Abstract excerpt
The International HapMap Consortium recently completed genotyping over 3.8 million single nucleotide polymorphisms (SNPs) in three major populations, and the results of studying patterns of linkage disequilibrium indicate that characterization of 300,000-500,000 tag SNPs is sufficient to provide good genomic coverage for linkage-disequilibrium-based association studies in many populations. These whole-genome...
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