Article
The Epstein-Barr virus (EBV) DNA polymerase accessory protein, BMRF1, activates the essential downstream component of the EBV oriLyt.
Virology - 31 Mar 1997
Zhang Q, Holley-Guthrie E, Ge J Q, Dorsky D, Kenney S
Abstract excerpt
The EBV DNA polymerase accessory protein, BMRF1, is an essential component of the viral DNA polymerase and is required for lytic EBV replication. In addition to its polymerase accessory protein function, we have recently reported that BMRF1 is a transcriptional activator, inducing expression of the essential oriLyt promoter, BHLF1. Here we have precisely mapped the BMRF1-response element in the BHLF1 promoter. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
