Interaction of glycoprotein gIII with a cellular heparinlike substance mediates adsorption of pseudorabies virus.

doi:10.1128/JVI.64.1.278-286.1990

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Article

Interaction of glycoprotein gIII with a cellular heparinlike substance mediates adsorption of pseudorabies virus.

Journal of virology - 1 Jan 1990

Mettenleiter T C, Zsak L, Zuckermann F, Sugg N, Kern H, Ben-Porat T

Abstract excerpt

Glycoprotein gIII is one of the major envelope glycoproteins of pseudorabies virus (PrV) (Suid herpesvirus 1). Although it is dispensable for viral growth, it has been shown to play a prominent role in the attachment of the virus to target cells, since gIII- deletion mutants are severely impaired...

Topics

Adsorption
Animals
Cell Line
Chromatography, Affinity
Heparin
Heparin Lyase
Herpesvirus 1, Suid
Kinetics
Mutation
Polysaccharide-Lyases
Viral Envelope Proteins
Viral Plaque Assay
Viral Proteins

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