Effect of polylysine on the early stages of infection of wild type pseudorabies virus and of mutants defective in gIII.

doi:10.1016/0042-6822(90)90301-7

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Article

Effect of polylysine on the early stages of infection of wild type pseudorabies virus and of mutants defective in gIII.

Virology - 1 Nov 1990

Zsak L, Mettenleiter T C, Sugg N, Ben-Porat T

Abstract excerpt

The main pathway of adsorption of pseudorabies virus (PrV) to its host cells is via interactions between viral glycoprotein gIII and a cellular heparin-like receptor. Mutants of PrV deficient in glycoprotein gIII adsorb by an alternative, slower pathway. Penetration into the cells of gIII- mutant...

Topics

Adsorption
Animals
Antibodies, Viral
Cell Line
Herpesvirus 1, Suid
Mutation
Neutralization Tests
Peptides
Polylysine
Viral Envelope Proteins

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