Cell surface proteoglycans are not essential for infection by pseudorabies virus.

doi:10.1128/JVI.69.6.3482-3489.1995

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Article

Cell surface proteoglycans are not essential for infection by pseudorabies virus.

Journal of virology - 1 Jun 1995

Karger A, Saalmüller A, Tufaro F, Banfield B W, Mettenleiter T C

Abstract excerpt

Cell surface proteoglycans, in particular those carrying heparan sulfate glycosaminoglycans, play a major role in primary attachment of herpesviruses to target cells. In pseudorabies virus (PrV), glycoprotein gC has been shown to represent the major heparan sulfate-binding virion envelope protein...

Topics

Animals
Cattle
Cell Line
Cell Membrane
Glycosaminoglycans
Herpesvirus 1, Suid
L Cells
Membrane Fusion
Mice
Mutation
Proteoglycans
Virulence

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