Article
Cell surface proteoglycans are not essential for infection by pseudorabies virus.
Journal of virology - 1 Jun 1995
Karger A, Saalmüller A, Tufaro F, Banfield B W, Mettenleiter T C
Abstract excerpt
Cell surface proteoglycans, in particular those carrying heparan sulfate glycosaminoglycans, play a major role in primary attachment of herpesviruses to target cells. In pseudorabies virus (PrV), glycoprotein gC has been shown to represent the major heparan sulfate-binding virion envelope protein (T. C. Mettenleiter, L. Zsak, F. Zuckermann, N. Sugg, H. Kern, and T. Ben-Porat, J. Virol. 64:278-286, 1990). Since...
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