Article
Differential allelic distribution of V-ets erythroblastosis virus E26 oncogene homolog2 (ETS2) functional polymorphisms in different group of patients.
Gene expression - 1 Jan 2010
Chatterjee Arpita, Dutta Samikshan, Mukherjee Sanjit, Mukherjee Nupur, Chandra Sharmila, Mukherjee Ashis, Sinha Swagata, Panda Chinmay Kumar, Chaudhuri Keya, Mukhopadyay Kanchan
Abstract excerpt
V-ets erythroblastosis virus E26 oncogene homolog2 (ETS2), located at chromosome 21 and overexpressed in Down's syndrome (DS), has known cancer regulatory functions. Because leukemia is of common occurrence in DS subjects while solid tumors are rare, we have explored the role of ETS2 functional genetic polymorphisms in this differential oncological development. In silico methods were used for identifying...
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