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Article

Exploratory investigation on functional significance of ETS2 and SIM2 genes in Down syndrome.

Disease markers - 1 Jan 2011

Chatterjee Arpita, Dutta Samikshan, Sinha Swagata, Mukhopadhyay Kanchan

Abstract excerpt

Trisomy of the 21{st} chromosome leads to an over dosage of several regulatory genes in Down syndrome (DS). Though allelic and genotypic combinations formed between genes are interesting, till date, this particular area has never been explored in DS. In the present investigation four SNPs in two transcription factors, Single minded 2 (SIM2) and V-ets erythroblastosis virus E26 oncogene homolog2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22048266
DOI: 10.3233/DMA-2011-0825
PMCID: PMC3826905

Genes

SIM2
ETS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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