Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p38MAPK/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infection

12 Sept 2023

Abstract excerpt

Autophagy plays an important role in recognizing and protecting cells from invading intracellular pathogens such as Salmonella. In this work, we investigated the role of p38MAPK/MK2 in modulating the host cell susceptibility to Salmonella infection. Inhibition of p38MAPK or MK2 led to a significant increase of bacterial counts in Salmonella infected mouse embryonic fibroblasts (MEFs), as well as in MK2-deficient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to CRISPR and Genetic Engineering
Share to Vibrio bacteria research studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37771590
DOI: 10.3389/fimmu.2023.1245443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p38MAPK/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infectionPMID 37771590Read ↗

Salmonella Interacts With Autophagy to Offense or DefenseSemantic proximity Read ↗

Autophagy and Ubiquitination in Salmonella Infection and the Related Inflammatory ResponsesSemantic proximity Read ↗

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection.Semantic proximity Read ↗

Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in MacrophagesSemantic proximity Read ↗

Restricting intracellular Salmonella proliferation by coordinating p-TBK1 mediated mitophagy and xenophagySemantic proximity Read ↗

TBK1 Mediates Crosstalk Between the Innate Immune Response and AutophagySemantic proximity Read ↗

Salmonella Typhimurium persistently infects host via its effector SseJ-induced PHB2-mediated mitophagySemantic proximity Read ↗

Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages.Semantic proximity Read ↗

Pyroptosis regulation by Salmonella effectorsSemantic proximity Read ↗

Interactions between Salmonella and host macrophages – Dissecting NF-κB signaling pathway responsesSemantic proximity Read ↗

Recruitment of TBK1 to cytosol‐invading Salmonella induces WIPI2‐dependent antibacterial autophagySemantic proximity Read ↗

Salmonella Enteritidis Effector AvrA Suppresses Autophagy by Reducing Beclin-1 ProteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.