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Article

Roles of Pim‐3, a novel survival kinase, in tumorigenesis

25 Apr 2011

Abstract excerpt

Pim-3 is a member of the Provirus integrating site Moloney murine leukemia virus (Pim) family, which belongs to the Ca(2+) /calmodulin-dependent protein kinase (CaMK) group and exhibits serine/threonine kinase activity. Similar to other members of the Pim family (i.e. Pim-1 and Pim-2), Pim-3 can prevent apoptosis and promote cell survival and protein translation, thereby enhancing cell proliferation of normal and...

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PMID: 21518143
DOI: 10.1111/j.1349-7006.2011.01966.x

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